Michael Owen (thigh) joins Ashley Young (toe), Ryan Giggs (hamstring), Chris Smalling (foot) and Tom Cleverley (ankle) on the sidelines.
Return: Nemanja Vidic will be back at the heart of Manchester United's defence
United, whose manager Sir Alex Ferguson will celebrate his 25th anniversary in charge of the club this weekend, have not lost at home to the Black Cats since 1968, whilst Steve Bruce has never recorded a victory as a manager against his old club.
Provisional squad: De Gea, Lindegaard, Amos, Jones, Rafael, Fabio, Ferdinand, Evans, Vidic, Valencia, Anderson, Park, Fletcher, Gibson, Nani, Diouf, Hernandez, Rooney, Berbatov, Welbeck.
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Source: Daily Mail
Source: Daily Mail