He limped through the closing stages of Saturday’s stalemate at Aston Villa.
O’Shea suffered a groin strain in the final 10 minutes at Villa Park after Sunderland had already used all of their three substitutes.
Gus Poyet: “It was a worry at the end.
“One second they said to me he was out and we were trying to switch things around.
“The next second, he managed to stay on the pitch limping, which was great for us.
“Credit to him and let’s hope it’s nothing serious.”
Valentin Roberge will almost certainly take O’Shea’s place in the starting XI if the Republic of Ireland international fails to recover.
PREMIER LEAGUE FIXTURES
Tuesday December 3
20:00 Crystal Palace v West Ham United
Wednesday December 4
19:45 Arsenal v Hull City
19:45 Liverpool v Norwich City
19:45 Man Utd v Everton
19:45 Southampton v Aston Villa
19:45 Stoke City v Cardiff City
19:45 Sunderland v Chelsea
19:45 Swansea City v Newcastle United
20:00 Fulham v Tottenham
20:00 West Brom v Manchester City
Sunderland Fixtures
Wednesday December 4
19:45 Premier League Sunderland v Chelsea
Saturday December 7
17:30 Premier League Sunderland v Tottenham
Saturday December 14
15:00 Premier League West Ham United v Sunderland
Tuesday December 17
19:45 League Cup - Qtr Sunderland v Chelsea
Saturday December 21
15:00 Premier League Sunderland v Norwich City
Thursday December 26
15:00 Premier League Everton v Sunderland
Saturday December 28
17:30 Premier League Cardiff City v Sunderland